Diets High in Fructose Inhibits the Appetite Hormone

A new animal study from the University of Florida, published August 2008 in the American Journal of Physiology — Regulatory, Integrative and Comparative Physiology, found that rats became leptin-resistant after being fed a high-fructose diet for six months. Leptin is the appetite-controlling hormone and leptin resistance has long been linked to obesity. This study and a number of other studies have shown that overconsumption of fructose may be an important factor in the United States’ obesity epidemic. This new study is the first to link fructose and leptin resistance.
The fructose-fed rats gained considerably more weight than rats that never received fructose when both groups of rats were switched to a high-fat diet.
“The surprising finding here was that increasing the amount of fructose in the diet without increasing the amount of calories led to leptin resistance and later exacerbated obesity when paired with a high-fat diet,” study senior author Philip J. Scarpace, a professor of pharmacology and therapeutics in the College of Medicine, said in a university news release.
“[Fructose] blocks leptin action most likely by blocking leptin entry into the brain,” study author Alexandra Shapiro, an assistant scientist in the department of pharmacology and therapeutics, explained in the news release.

“If these findings are applicable to humans, then there could be consequences of eating a diet high in fructose, but only if you also consume an excessive amount of calories,” Scarpace said.

Learn More About Low Carb Articles & Research

The Guide to Atkins Bars

Learn about Atkins most popular protein bars and how they can help support your low carb lifestyle or reach your weight loss goals. Between a busy work week or a hectic schedule at home, trying to reach your nutrition goals can feel like another chore on your to-do list. That’s why finding quality protein bars to

Read More »

35 Easy Keto Dinner Recipe Ideas

Keto Beef Recipes | Keto Pork Chop Recipes | Keto Chicken Recipes | Keto Shrimp Recipes | Vegetarian Keto Recipes | Keto Soup Recipes | Keto Crockpot Recipes | Keto Air Fryer Recipes | Keto Instant Pot® Recipes Whether you’re just getting started with keto or need some new additions to your recipe rotation, it’s

Read More »

20 Keto Breakfast Recipes & Ideas

Keto Breakfast Smoothie Recipes | Keto Breakfast Sandwich Ideas | East Keto Breakfast Recipes with Eggs | Keto Breakfast Casserole Recipes | Keto Breakfast without Eggs Following a ketogenic diet doesn’t mean you should skimp on a delicious breakfast or eat the same thing every day. In fact, Atkins’ take on keto diets emphasize optimal

Read More »